More than 190 full and temporary positions are being created in Dublin, Cork, Donegal and Meath in four separate job announcements today.
Fifty jobs are being created in Kells by two American tech firms in a joint venture, while Ward Solutions is creating 16 jobs in Dublin.
Discount supermarket chain Aldi has announced it is opening new stores in Ballybofey and Macroom, creating 40 new jobs
Meanwhile, 30 full time jobs will come on stream when a new distillery and visitor centre are built at the Dublin Whiskey Company in the Liberties.
More than 60 workers will be employed during the construction phase early next year.
Managing Director of the Dublin Whiskey Company Marie Byrne said: "There's a real opportunity to showcase a real, working distillery. We're hoping to bring people into the Liberties for the first time (with this initiative)," she said.