She stars opposite Matt Damon, Ben Affleck and Adam Driver in the historical drama.
In the film, Affleck’s King Charles VI declares that Knight Jean de Carrouges (Damon) settle his dispute with his squire (Driver) by challenging him to a duel.
Comer plays Damon’s wife, Marguerite de Carrouges.
Arriving on set at Cahir Castle in Co Tipperary, she can be seen sporting elaborate plaits, as she wore a black poncho over a peach coloured gown and carried a tote bag while wearing a plastic face shield.
The film is directed by Ridley Scott and the script was penned by Damon and Affleck, who previously won an Oscar for their Good Will Hunting screenplay.
The film also stars Dame Harriet Walter and Nathaniel Parker.
Driver could also be seen wearing a black face covering and a black hooded coat, with locks of his long black hair hanging loose around his face.
The Last Duel is expected to be released in 2021.