The trial of his libel claim garnered worldwide attention as it unfolded over three weeks in July at the Royal Courts of Justice in London.
Mr Depp, 57, will find out the outcome of his case as trial judge Mr Justice Nicol delivers his long-awaited ruling.
Both he and Ms Heard, 34, attended the trial, which featured days of high drama, claims of brutal violence and sensational revelations about their tempestuous relationship.
The court heard evidence over 16 days from both stars, friends and relatives of the couple and several former and current employees.
Mr Depp spent around 20 hours in the witness box over five days, facing intense questioning about his Hollywood lifestyle, his use of drink and drugs, allegations of violence and his friendships and associations with famous faces including Rolling Stones guitarist Keith Richards and musician Sir Elton John.
In closing arguments, the actor’s barrister David Sherborne said Mr Depp’s case was about vindication.
He said: “What is important to Mr Depp is clearing his name of these appalling allegations, expanded on as it has been over the last four years, as a result of which he has lost nothing less than everything, he would say.
“When I say he has lost everything, to him obviously everything is his reputation. This is not about money, this is vindicating him.”
Sasha Wass QC, for NGN, argued there is “no doubt that Mr Depp regularly and systematically abused his wife.
“The characterisation that he is a wife-beater is entirely truthful.”
As the trial drew to a close, Ms Heard stood outside on the steps of the High Court and said she stood by her evidence and would “place her faith in British justice”.
In an April 2018 column, The Sun’s executive editor Dan Wootton asked how Harry Potter author JK Rowling could be “genuinely happy” after Mr Depp was cast in the latest film in the Fantastic Beasts spin-off franchise. The role was offered despite the allegations by Ms Heard.
The Pirates Of The Caribbean star denies ever having been violent to Ms Heard and claims the article included quotes from alleged victims of disgraced film producer Harvey Weinstein. He said these were designed to “finish his career” by linking the allegations against him to the #MeToo and Time’s Up movements.
NGN is defending the article as true and says Mr Depp was “controlling and verbally and physically abusive towards Ms Heard, particularly when he was under the influence of alcohol and/or drugs” between early 2013 and May 2016 when the couple split.
Mr Justice Nicol will give his ruling at 10am on Monday. The judgment will be delivered remotely and is not known whether any of the parties will attend court.
