Some 4,674 cases have been reported in the last seven days, bringing the overall total number of cases confirmed in the region to 17,110.
One further death has been reported by the department, bringing the toll to 587.
The figures come as Taoiseach Micheál Martin spoke with British prime minister Boris Johnson this morning about the escalating infection figures in the region.
Both leaders expressed concern about the growing number of cases in the North and agreed to monitor the situation closely.
Mr Johnson’s official spokesman said: “It wasn’t a call about any aspects of Brexit.
“It was about the response to Covid and ensuring that the United Kingdom Government and the Irish Government can work closely together on helping to combat the spread of the virus on the island of Ireland.”
Stormont meeting
Amid soaring figures, a hike in coronavirus fines and extending the places where face coverings are mandatory in the North will be considered by Stormont ministers today.
Justice minister Naomi Long is due to present the outcome of a rapid review into penalties and enforcement of the Covid-19 regulations at Thursday afternoon’s executive meeting.
It is understood a proposal to increase the fine that accompanies a fixed-penalty notice for a rule breach from £60 (€66) to £200 (€220).
The Executive Office is also due to present proposals around extending the public settings where face coverings should be mandatory.
If agreed, this would see the law widened to cover places such as office spaces, banks and building societies.
Coverings are already mandatory in shops and on public transport.
As Northern Ireland continues to experience rocketing coronavirus infection rates, the Derry City and Strabane Council area - which has one of the highest infection rates in the UK - is currently subject to additional restrictions.
While ministers are due to discuss the potential extension of restrictions to other council areas with high rates, such as Newry, Mourne and Down council, they are not anticipated to make final decisions on Thursday.
It comes as a second appeal has been made for health care staff to come forward to boost the number of workers in the battle against coronavirus in the region.
The first appeal in March saw thousands of applications and resulted in 1,702 doctors, nurses and other ancillary staff joining the work force for the first surge of Covid-19.
