Gardaí from the Tipperary Divisional Drugs Unit conducted the search at a residence in Holycross yesterday afternoon which led to the seizure of drugs and cash valued at €21,500.
Suspected cannabis, MDMA, amphetamine and cocaine were seized with an estimated value totalling €16,100.
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Cash to the value of €5,400 was also seized during the course of the operation.
A female in her 30s was arrested at the scene and taken to Templemore Garda Station where she was detained under Section 4 of the Criminal Justice Act, 1984.
She has since been released without charge and a file is being prepared for the Director of Public Prosecutions in relation to this matter.
Gardaí have said investigations are ongoing.