Minister for Enterprise Simon Coveney has accused Israel of behaving like a "monster" and a "rogue state".
Pressure is mounting on Israel over the ongoing conflict in Gaza amid appeals for a ceasefire.
China has joined growing international calls for Israel to halt military operations in Gaza following a raid in which two hostages were rescued and scores of Palestinians killed.
Israel has signalled its ground offensive may soon target Rafah, the town where the hostages were freed by the raid.
US president Joe Biden said innocent people in Rafah need to be protected.
Speaking before Tuesday's Cabinet meeting in Dublin, Mr Coveney said Israel needed to start listening.
"Where we are now is we are witnessing Israel behaving like a rogue state, quite frankly. They're ignoring the International Court of Justice (ICJ)," he said.
"They seem now to even be ignoring their closest allies in countries like the United States in the UK, who are clearly calling for restraint, looking for the basis of a ceasefire, or wanting to work with Israel to bring an end to this savagery that is continuing in Gaza."
Last month, the ICJ ordered Israel to prevent acts of genocide against the Palestinians and do more to help civilians, although it stopped short of ordering a ceasefire as requested by the plaintiff South Africa.
Mr Coveney said the international community needed to be stronger on the issue of Gaza and pushed Israel's allies to be more insistent that the attacks on civilians in Gaza must end.
"The truth is that the European position has effectively moved towards the Irish position, you know, over the last number of weeks. There are very few countries now not calling for a ceasefire," he said.
"There are very few countries now not wanting to put pressure on Israel to pull back and look for a peace agreement that can prevent soldiers moving into a city that has one and a half million people in it, and it's going to be impossible to avoid massive civilian casualties, yet again, in a small piece of land that's already seen 28,000 people dead over the last number of months.
"So actually, the Irish position has been an effective one."
Mr Coveney said the Government led the way on international calls for a ceasefire and said Israel must not be allowed to continue its killing of civilians in response to the October 7th attack.
"I've been to the Gaza Strip on five or six occasions. The suffering in that area before this round of conflict was significant. But what we've seen in the last number of months must be unacceptable for the international community. You know, it is not acceptable effectively to behave like a monster to defeat a monster, which is what Israel is now doing.
"Ireland has been using its voice internationally to try to build consensus within the European Union to stop this madness, and we need to continue to do that forcefully."
