Leinster are welcoming back 11 players who featured for Ireland during their run to Six Nations success to start against the Bulls at the RDS in Dublin on Good Friday.
For the URC clash, Jordan Larmour, James Lowe, Rob Russell, Robbie Henshaw and Harry Byrne start in the back line, while in the forwards there's Cian Healy and Ronan Kelleher in the front row.
Joe McCarthy in the second row and Ryan Baird, Josh van der Flier and Jack Conan named in a strong backrow.
The Bulls have made six changes from the match against Dragons last weekend, with openside flanker Elrigh Louw returning to the starting line-up after a shoulder injury.
Bulls head coach Jake White says the match will be a great opportunity to test progress of his side.
The match is at 7.35pm on TG4 and Premier Sports.
LEINSTER (v Bulls): Jordan Larmour; Rob Russell, Robbie Henshaw, Jamie Osborne, James Lowe; Harry Byrne, Luke McGrath (capt); Cian Healy, Rónan Kelleher, Michael Ala’alatoa; Ross Molony, Joe McCarthy; Ryan Baird, Josh van der Flier, Jack Conan.