Kamna accelerated away from Richard Carapaz at the top of the penultimate climb of the 164km stage from La Tour-du-Pin to take his first career Grand Tour win.
The main group of contenders, happy to let a 23-strong breakaway have their fun up ahead, rolled in more than 17 minutes later, with Roglic and second-placed Tadej Pogacar locked together to maintain the 40-second gap between them.
🇨🇴 @SupermanlopezN launches himself ahead of 🇸🇮 @rogla and @TamauPogi to cross the line first. They each count the same time.
Malgré une attaque dans les derniers mètres pour finir devant les deux slovènes, 🇨🇴 @SupermanlopezN n'est pas parvenu à reprendre du temps.#TDF2020 pic.twitter.com/R9wDaoS9tY— Tour de France™ (@LeTour) September 15, 2020
There was no change at the top of the overall standings, with Rigoberto Uran third ahead of fellow Colombian Miguel Angel Lopez in fourth and Adam Yates in fifth, with Wednesday’s stage from Grenoble to the Col de la Loze above Meribel expected to prove more decisive.
Last year’s winner Egan Bernal, having dropped out of contention when he was distanced on the Grand Colombier on Sunday, was again off the pace and rode home in the grupetto alongside the sprinters and other stragglers down the mountain, at least managing to smile and joke as he did so.
Ineos had instead pinned their hopes on a stage win, with Andrey Amador and Pavel Sivakov joining Carapaz in a large group that was allowed up the road.
That group broke up decisively on the climb up the Montee de Saint-Nizier-du-Moucherotte a little over 20km from the line, with Carapaz attacking first but Kamna able to follow and then accelerate away on the valley road to the final ramp to the line.
🇫🇷 #TDF2020
FINALLY!!!@lennardkaemna takes stage 16 @LeTour 👏👏👏 pic.twitter.com/ClWYKsCgWw— BORA – hansgrohe (@BORAhansgrohe) September 15, 2020
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Kamna, 24, took a stage win at the Criterium du Dauphine last month before taking second place to Dani Martinez on stage 13 of the Tour on Friday.
“I’m feeling great,” Kamna said. “It’s an absolutely awesome day for me now. It was a fight from the beginning on and I knew I had to make it to the finish alone. When I saw Carapaz upping the speed I thought, ‘Now is the moment to go’ and I just went all in to the end.
“It’s a big, big, big relief for the team and for me. I can almost not imagine it. The step I made this year is huge and I’m so pleased to win today.”
Ireland's Nicholas Roche was also in the break and came home in eighth place on the stage.
#TDF2020
Another good ride from the guys today and a double top 10 finish for us! @TiesjBenoot crossed the line in 7th with @nicholasroche just behind him in 8th.👌🏻 #KeepChallenging pic.twitter.com/W7ykrKRSLb— Team DSM (@TeamDSM) September 15, 2020
“You start the stage with the dream of winning another stage in the Tour de France but also you cannot be too greedy, you’re competing against some of the best riders on the planet,” roche said.
“Sometimes it works, sometimes not, but Lenny today showed he was the strongest on the climb. We’ve seen he’s strong already since the beginning of the Tour so he’s a well-deserved winner.”
Neither Sam Bennett nor Peter Sagan made it into the early attacks so Bennett remains 45 points ahead of the former world champion in the battle for green, but Matteo Trentin won the intermediate sprint to pick up 20 points and close his own deficit to Bennett to 60.