The moment marked a political high point for Mr Biden, who had sought the presidency twice before and is now cemented as the embodiment of Democrats’ desire to defeat Mr Trump in autumn.
A roll call of convention delegates formalised what has been clear for months since Mr Biden took the lead in the primary elections chase for the nomination.
It came as he worked to demonstrate the breadth of his coalition for a second consecutive night at the virtual national convention.
Former president Bill Clinton and ex-secretary of state John Kerry – and former Republican secretary of state Colin Powell – were among the heavy hitters emphasising the importance of leadership.
Mr Clinton said: “Donald Trump says we’re leading the world. Well, we are the only major industrial economy to have its unemployment rate triple.
“At a time like this, the Oval Office should be a command centre. Instead, it’s a storm centre. There’s only chaos.”
Tuesday’s speaking programme underscored Mr Biden’s challenge as he seeks to inspire a new generation of voters.
But just 77 days before the election, Mr Biden has neither history nor enthusiasm on his side.
Only one incumbent president has been defeated in the last four decades and Mr Biden’s supporters consistently report they are motivated more by opposition to Mr Trump than excitement about Biden, a 77-year-old lifelong politician.
That deficit could hurt turnout among less consistent voters, particularly minorities and younger voters, whom Biden needs to show up in great numbers this fall.
Mr Biden formally captured his party’s presidential nomination after being nominated by three people, including two Delaware lawmakers and 31-year-old African American security guard who became a viral sensation after blurting out “I love you” to Biden in a New York City lift.
Meanwhile, Mr Trump continued to court battleground voters in an effort to distract from his opponent’s convention.
Appearing in Arizona near the Mexican border earlier in the day, the Republican president claimed a Biden presidency would trigger “a flood of illegal immigration like the world has never seen”.
Such divisive rhetoric, which is not supported by Mr Biden’s positions, has become a hallmark of Mr Trump’s presidency, which has inflamed tensions at home and alienated longstanding allies around the world.
Mr Kerry said in an excerpt of his remarks: “Joe understands that none of the issues of this world – not nuclear weapons, not the challenge of building back better after Covid, not terrorism and certainly not the climate crisis – none can be resolved without bringing nations together.”
