A leading adviser to the World Health Organisation has described the unprecedented outbreak of monkeypox in developed countries as “a random event” that might be explained by sexual behaviour at two recent raves.
Dr David Heymann, who formerly headed the WHO’s emergencies department, told the Associated Press that the leading theory out of many put forward to explain the spread of the disease was sexual transmission at raves in Europe.
Monkeypox has not previously triggered widespread outbreaks beyond Africa, where it is endemic in animals.
“We know monkeypox can spread when there is close contact with the lesions of someone who is infected, and it looks like sexual contact has now amplified that transmission,” said Dr Heymann.
That marks a significant departure from the disease’s typical pattern of spread in central and western Africa, where people are mainly infected by animals like wild rodents and primates and outbreaks have not spilled across borders.
Health officials say most of the known cases in Europe have been among men who have sex with men, but anyone can be infected through close contact with a sick person, their clothing or bedsheets. Scientists say it will be difficult to establish whether the spread is being driven by sex or merely close contact.
“By nature, sexual activity involves intimate contact, which one would expect to increase the likelihood of transmission, whatever a person’s sexual orientation and irrespective of the mode of transmission,” said Mike Skinner, a virologist at Imperial College London.
On Monday, the European Centre for Disease Prevention and Control’s director, Andrea Ammon, said “the likelihood of further spread of the virus through close contact, for example during sexual activities among persons with multiple sexual partners, is considered to be high”.
#JustPublished!
Rapid Risk Assesment on the #monkeypox multi-country outbreak.
Full details in the thread below and the report:https://t.co/fIRfGdraMP https://t.co/RIsTRgVgRQ— ECDC (@ECDC_EU) May 23, 2022
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The WHO has recorded more than 90 cases of monkeypox in a dozen countries including Canada, Spain, Israel, France, Switzerland, the US and Australia. On Monday, Denmark announced its first case, Portugal revised its total up to 37, Italy reported one further infection and Britain added 37 more cases.
Germany has four confirmed cases linked to exposure at “party events… where sexual activity took place” in Spain’s Canary Islands and in Berlin, according to a government report obtained by the AP.
Madrid’s senior health official said on Monday that the Spanish capital had 30 confirmed cases. Enrique Ruiz Escudero said authorities are investigating possible links between a recent Gay Pride event in the Canary Islands, which drew 80,000 people, and cases at a Madrid sauna.
The monkeypox cases so far have been mild, with no deaths reported. Typically, the virus causes fever, chills, rash and lesions on the face or genitals. Most people recover within several weeks without requiring hospital treatment.
Vaccines against smallpox, a related disease, are effective in preventing monkeypox and some antiviral drugs are being developed. In recent years, the illness has been fatal in up to 6% of infections.
🔴 What is #monkeypox?
🔴 What are the symptoms?
🔴 How does it spread from person to person?
🔴 Where in the world is there currently a risk of monkeypox?
🔴 Who is at risk of catching monkeypox?
WHO Q&A on monkeypox https://t.co/tMKv3FHw4g pic.twitter.com/XN9e49yBNG— World Health Organization (WHO) (@WHO) May 20, 2022
Dr Heymann chaired an urgent meeting of the WHO’s advisory group on infectious disease threats on Friday to assess the outbreak and said there was no evidence to suggest monkeypox had mutated into a more infectious form.
The UN agency said the outbreak is “a highly unusual event” and said the fact that cases are being seen in so many countries suggests the virus may have been silently spreading for some time. The agency’s Europe director warned that festivals and parties could accelerate spread.
At a public session on Monday, WHO officials described the outbreak as “containable” and cautioned against stigmatising affected groups, saying the disease can infect anyone.
The agency said the cases appeared to be linked to a monkeypox virus first detected in cases exported from Nigeria to Britain, Israel and Singapore in 2018 and 2019.
Authorities in Britain, Spain and Portugal have said most of the cases identified so far were in young men whose infections were picked up when they sought help for lesions at sexual health clinics.
Dr Heymann, who is also a professor of infectious diseases at the London School of Hygiene and Tropical Medicine, said the monkeypox outbreak was likely to be a random event that might be traceable to a single infection.
“It’s very possible there was somebody who got infected, developed lesions on the genitals, hands or somewhere else, and then spread it to others when there was sexual or close physical contact,” he said. “And then there were these international events that seeded the outbreak around the world, into the US and other European countries.”
He emphasised that the disease is unlikely to trigger widespread transmission.
“This is not Covid,” he said. “We need to slow it down, but it does not spread in the air and we have vaccines to protect against it.”
Dr Heymann said studies should be conducted rapidly to determine if monkeypox could be spread by people without symptoms and that populations at risk of the disease should take precautions to protect themselves.
