Streets and homes were flooded with sewage water in the port city of Karachi, where the drainage and sewage systems are outdated.
Of the total of the rain-related casualties, 31 deaths were reported in southern Sindh province, while 23 people died in the province of Khyber Pakhtunkhwa, according to the agency.
It said 15 deaths were reported in southwestern Baluchistan province and eight in Punjab province. Thirteen more people died elsewhere in northern Pakistan, including three in the Pakistan-administered sector of Kashmir.
The rains are expected to continue this week in Karachi, where Prime Minister Imran Khan earlier this month sent troops to help local authorities in pumping out rainwater from inundated residential areas.
Every year, many cities in Pakistan struggle to cope with the annual monsoon deluge, drawing criticism about poor planning. The monsoon season runs from July to September.