The first European to blast off in a rocket and capsule designed by Elon Musk’s SpaceX is due to dock at the International Space Station on Saturday morning.
Frenchman Thomas Pesquet is the first European Space Agency (ESA) astronaut to ride in the Crew Dragon spacecraft, which launched from Nasa’s Kennedy Space Centre in Florida just before 11am UK time on Friday.
Also on board is Nasa’s Shane Kimbrough and Megan McArthur and Jaxa’s (Japan Aerospace Exploration Agency) Akihiko Hoshide on his second mission to the ISS.
It is the third launch for Nasa’s Commercial Crew programme, which relies on private sector companies operating from the US, in less than a year.
Nasa was previously reliant on the Soyuz shuttle programme for more than a decade.
The “recycled” Crew Dragon capsule and Falcon rocket combination sent four astronauts to the ISS last November and the capsule transported and returned two astronauts during the first crewed SpaceX flight last May.
The capsule is due to come into dock at 10.10am Irish time – almost 24 hours after launch.
The crew will replace Nasa’s Michael Hopkins, Victor Glover and Shannon Walker, and Jaxa’s Soichi Noguchi, who are scheduled to return to Earth next Wednesday in another SpaceX capsule.
For her debut mission, Ms McArthur is flying on the same seat as her husband Bob Behnken did for SpaceX’s debut crew flight in May last year.
After a six-month stay, the Crew-2 astronauts will leave the ISS in October and splashdown in the Atlantic Ocean off the coast of Florida.
David Parker, director of human and robotic exploration at the ESA, said: “Thomas’ mission is part of a sequence that is taking us on a journey that will, one day, end up with boots on Mars, the red planet.
“But right now, Mars is only a destination for our robots.
“Beyond the space station, one of the things we are doing is preparing for the return to the Moon, or going forward to the Moon, to explore it properly this time.
“So Europe is building the power propulsion for Orion – the new deep spacecraft that will take humans to the Moon. We have three seats aboard that are already planned.”
He added: “We will learn then on the Moon how to take that much bigger leap eventually to the surface of Mars.”
Mr Pesquet is due to command the ISS during the final month of his six-month mission.
Josef Aschbacher, the ESA’s director general, described the launch as “an emotional moment”.
He said: “As the director general of ESA, I am very happy to see Thomas now flying to the ISS. All of us at ESA are very excited to see this happening.
Mr Aschbacher added: “SpaceX has done an incredible job.”